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CDC Issues Updated Opioid Prescribing Guidelines for Chronic Pain Management

National Desk
April 30, 2026

Why it matters locally: South Carolina has been significantly affected by the opioid crisis. These updated guidelines could influence prescribing practices within the state and potentially impact efforts to reduce opioid-related harms and overdose deaths.


Atlanta, GA – The Centers for Disease Control and Prevention (CDC) today released updated recommendations regarding the prescription of opioid medications for the management of chronic pain. These guidelines are intended for use by healthcare providers when prescribing opioids for adult outpatients experiencing chronic pain, excluding those receiving cancer treatment, palliative care, or end-of-life care. The CDC states the updated guidelines are a part of the U.S. government's ongoing response to the rise in overdose deaths. The recommendations provide clinical guidance to healthcare providers to aid informed decision-making regarding opioid prescribing. The guidelines address various aspects of opioid prescribing, including: * Determining when to initiate or continue opioid therapy for chronic pain. * Opioid selection, dosage, duration, follow-up, and discontinuation. * Assessing risk and addressing potential harms of opioid use. The new guidelines emphasize a patient-centered approach to pain management, prioritizing non-opioid therapies and shared decision-making between clinicians and patients. The CDC encourages healthcare providers to consider the individual circumstances and needs of each patient when making treatment decisions. Healthcare professionals are advised to consult the full CDC guideline document for detailed recommendations and implementation strategies. The document is available on the CDC website. The CDC stated that the guidelines are intended to be flexible and adaptable to diverse clinical settings and patient populations.

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