FDA Approves Oral PCSK9 Inhibitor for Cholesterol Reduction

Why it matters locally: Maine residents managing hypercholesterolemia will now have access to a new oral treatment option, Lipfendra, approved by the FDA. This provides an additional tool for healthcare providers across the state to help patients reduce LDL-C levels.

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WASHINGTON – The U.S. Food and Drug Administration (FDA) has approved Lipfendra (enlicitide) for the reduction of low-density lipoprotein cholesterol (LDL-C) in adults with hypercholesterolemia. This medication represents the first oral inhibitor of proprotein convertase subtilisin/kexin type 9 (PCSK9). Doctors will prescribe Lipfendra as an addition to diet and exercise regimens. The FDA's decision provides a new treatment option for individuals working to manage their cholesterol levels.