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Eli Lilly Drug Retatrutide Shows Weight Loss in Type 2 Diabetes Trial

Eli Lilly's experimental drug retatrutide led to notable weight reduction in individuals with Type 2 diabetes, according to new trial results. Participants in the study, published in The Lancet, experienced an average loss of up to 60 pounds.

09/30/2026 · Massachusetts edition

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Why it matters locally: The promising results for Eli Lilly's new diabetes drug could significantly impact the roughly 1 in 10 adults in Massachusetts who have been diagnosed with diabetes, offering a new treatment option for weight management alongside their condition.

Eli Lilly's experimental drug retatrutide led to significant weight loss among individuals with Type 2 diabetes. Participants in a late-stage clinical trial lost up to 60 pounds, which represented approximately 23% of their body weight. Researchers published the findings from the study in The Lancet on Tuesday. The results detail the effects of retatrutide, a GLP-1 receptor agonist, in individuals diagnosed with Type 2 diabetes.

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