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CDC Study Links Opioid Painkiller Use in Early Pregnancy to Increased Risk of Birth Defects

A new study by the Centers for Disease Control and Prevention indicates a correlation between opioid painkiller use during early pregnancy and a modest increase in birth defect risk. The research focused on drugs like codeine, oxycodone, and hydrocodone. The findings do not establish a causal relationship.

06/11/2026 · Wisconsin edition

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A study by the Centers for Disease Control and Prevention (CDC) suggests that women who used opioid painkillers shortly before or during early pregnancy faced a slightly elevated risk of having babies with birth defects. The research examined the potential effects of drugs such as codeine, oxycodone, and hydrocodone.

The CDC researchers analyzed data to identify potential links between specific opioid medications and the occurrence of birth defects. Researchers emphasized the increased risk was modest. The study accounted for other factors that could influence birth defect rates.

The findings do not prove that opioid painkillers directly cause birth defects. Further research is needed to fully understand the nature and magnitude of the association. The CDC recommends women who are pregnant or planning to become pregnant discuss pain management options with their healthcare providers.

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